BDBM50171539 4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine-3-carboxylic acid hydroxyamide::CHEMBL370129

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSCC1C(=O)NO

InChI Key InChIKey=KQEHQRICYJKJLB-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50171539   

LigandPNGBDBM50171539(4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171539(4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171539(4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine...)
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against matrix metallopeptidase 9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171539(4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine...)
Affinity DataIC50: 148nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171539(4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine...)
Affinity DataIC50: 148nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171539(4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171539(4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171539(4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine...)
Affinity DataIC50: 3nMAssay Description:Inhibition of TACE (unknown origin) using fluorogenic LAQAVRSSSR peptide as a substrate by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article