BDBM50171535 4-Acetyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL195948

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(C)=O

InChI Key InChIKey=VJCSPSPTFYXXJB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50171535   

LigandPNGBDBM50171535(4-Acetyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-piper...)
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171535(4-Acetyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-piper...)
Affinity DataIC50: 357nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171535(4-Acetyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-piper...)
Affinity DataIC50: 88nMAssay Description:Inhibitory activity against matrix metallopeptidase 9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171535(4-Acetyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-piper...)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171535(4-Acetyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-piper...)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against matrix metallopeptidase 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50171535(4-Acetyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-piper...)
Affinity DataIC50: 357nMAssay Description:Inhibitory activity against matrix metallopeptidase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171535(4-Acetyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-piper...)
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against TACE[ADAM metallopeptidase domain 17] in isolated enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed