BDBM50171524 (E)-4-Dimethylamino-but-2-enoic acid [4-(3-iodo-phenylamino)-quinazolin-6-yl]-amide::CHEMBL189779

SMILES CN(C)C\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(I)c3)c2c1

InChI Key InChIKey=MCFYGOURGHBNOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171524   

TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171524((E)-4-Dimethylamino-but-2-enoic acid [4-(3-iodo-ph...)
Affinity DataIC50: 5nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171524((E)-4-Dimethylamino-but-2-enoic acid [4-(3-iodo-ph...)
Affinity DataIC50: 5nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171524((E)-4-Dimethylamino-but-2-enoic acid [4-(3-iodo-ph...)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed