BDBM50171519 CHEMBL365805::N-[4-(3-Bromo-phenylamino)-7-(4-methyl-piperazin-1-yl)-quinazolin-6-yl]-acrylamide

SMILES CN1CCN(CC1)c1cc2ncnc(Nc3cccc(Br)c3)c2cc1NC(=O)C=C

InChI Key InChIKey=DYEVORTZJPUZJF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171519   

TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171519(N-[4-(3-Bromo-phenylamino)-7-(4-methyl-piperazin-1...)
Affinity DataIC50: 250nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 50-250 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171519(N-[4-(3-Bromo-phenylamino)-7-(4-methyl-piperazin-1...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171519(N-[4-(3-Bromo-phenylamino)-7-(4-methyl-piperazin-1...)
Affinity DataIC50: 500nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed