BDBM50171255 CHEMBL194389::[3-Chloro-4-(pyridin-2-ylmethoxy)-phenyl]-(5-methoxy-quinazolin-4-yl)-amine

SMILES COc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12

InChI Key InChIKey=URQBZIUFPRGLCE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171255   

TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50171255([3-Chloro-4-(pyridin-2-ylmethoxy)-phenyl]-(5-metho...)
Affinity DataIC50: 440nMAssay Description:Inhibitory concentration against EGFR kinase phosphorylation using synthetic peptide as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50171255([3-Chloro-4-(pyridin-2-ylmethoxy)-phenyl]-(5-metho...)
Affinity DataIC50: 24nMAssay Description:Inhibitory concentration against erbB2 kinase phosphorylation using synthetic peptide as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed