BDBM50171251 (3-Chloro-4-methoxy-phenyl)-[5-(1-methyl-piperidin-4-yloxy)-quinazolin-4-yl]-amine::CHEMBL197525

SMILES COc1ccc(Nc2ncnc3cccc(OC4CCN(C)CC4)c23)cc1Cl

InChI Key InChIKey=WWZJQIRRGMAENV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171251   

TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50171251((3-Chloro-4-methoxy-phenyl)-[5-(1-methyl-piperidin...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory concentration against EGFR kinase phosphorylation using synthetic peptide as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50171251((3-Chloro-4-methoxy-phenyl)-[5-(1-methyl-piperidin...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration against erbB2 kinase phosphorylation using synthetic peptide as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed