BDBM50171249 (6,7-Dimethoxy-quinazolin-4-yl)-[3-methyl-4-(pyridin-2-ylmethoxy)-phenyl]-amine::CHEMBL371888

SMILES COc1cc2ncnc(Nc3ccc(OCc4ccccn4)c(C)c3)c2cc1OC

InChI Key InChIKey=NDHNEUUBLJKLCP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171249   

TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50171249((6,7-Dimethoxy-quinazolin-4-yl)-[3-methyl-4-(pyrid...)
Affinity DataIC50: 59nMAssay Description:Inhibitory concentration against EGFR kinase phosphorylation using synthetic peptide as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50171249((6,7-Dimethoxy-quinazolin-4-yl)-[3-methyl-4-(pyrid...)
Affinity DataIC50: 56nMAssay Description:Inhibitory concentration against erbB2 kinase phosphorylation using synthetic peptide as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed