BDBM50171234 CHEMBL365751::[2-(5-Chloro-2-methyl-1H-indol-3-yl)-ethyl]-dimethyl-amine

SMILES Cc1c(c2cc(ccc2[nH]1)Cl)CCN(C)C

InChI Key InChIKey=KSYMELKKLOFABL-UHFFFAOYSA-N

Data  4 KI  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50171234   

Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171234([2-(5-Chloro-2-methyl-1H-indol-3-yl)-ethyl]-dimeth...)
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 6(Human)
Carlsson Research

Curated by ChEMBL
LigandPNGBDBM50171234([2-(5-Chloro-2-methyl-1H-indol-3-yl)-ethyl]-dimeth...)
Affinity DataEC50:  45nMAssay Description:Agonist activity at 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 6(Rat)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50171234([2-(5-Chloro-2-methyl-1H-indol-3-yl)-ethyl]-dimeth...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H] lysergic acid diethylamide from rat 5-HT6 receptor transfected in HEK293 cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2B(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50171234([2-(5-Chloro-2-methyl-1H-indol-3-yl)-ethyl]-dimeth...)
Affinity DataKi:  245nMAssay Description:Binding affinity to 5-HT2B receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50171234([2-(5-Chloro-2-methyl-1H-indol-3-yl)-ethyl]-dimeth...)
Affinity DataKi:  290nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50171234([2-(5-Chloro-2-methyl-1H-indol-3-yl)-ethyl]-dimeth...)
Affinity DataKi:  300nMAssay Description:Binding affinity to human recombinant alpha2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed