BDBM50171223 CHEMBL195551::Cyclic sulfamide

SMILES CC(=O)N1CCN(C\C=C\c2ccc3C[C@@H]4CC[C@H](Cc3c2)[C@@]42CN(CC(F)(F)F)S(=O)(=O)N2)CC1

InChI Key InChIKey=VAOKILNPRXTGKB-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171223   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL

LigandBDBM50171223(Cyclic sulfamide | CHEMBL195551)Copy SMILESCopy InChI

Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against gamma-secretase in whole cell SH-SY5Y assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
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