BDBM50171213 CHEMBL194788::Cyclic sulfamide

SMILES Clc1ccc(s1)S(=O)(=O)NC1[C@H]2CC[C@@H]1Cc1cc(\C=C\CN3CCOCC3)ccc1C2

InChI Key InChIKey=JLUUIRBCSWTDEQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171213   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL

LigandBDBM50171213(Cyclic sulfamide | CHEMBL194788)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against gamma-secretase in whole cell SH-SY5Y assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
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