BDBM50171209 CHEMBL194680::N-propyl-N'-[(1R,10S)-tricyclo[8.2.1.0~3,8~]trideca-3,5,7-trien-13-yl]sulfamide::propyl({[(1R,10S,13R)-tricyclo[8.2.1.0^{3,8}]trideca-3,5,7-trien-13-yl]sulfamoyl})amine
SMILES CCCNS(=O)(=O)N[C@@H]1[C@H]2CC[C@@H]1Cc1ccccc1C2
InChI Key InChIKey=PZOPLWFFHZYNSY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50171209
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 132nMAssay Description:Inhibitory concentration against gamma-secretase in whole cell SH-SY5Y assayMore data for this Ligand-Target Pair