BDBM50171149 (S)-2-tert-Butyl-8-oxo-5,6,7,8-tetrahydro-1H-1,4,7a-triaza-s-indacene-7-carboxylic acid ((S)-2-hydroxy-5-oxo-tetrahydro-furan-3-yl)-amide::CHEMBL198974

SMILES CC(C)(C)c1cc2nc3CC[C@@H](C(=O)N[C@H]4CC(=O)OC4O)n3c(O)c2n1

InChI Key InChIKey=JFXZWAZFKMNDQZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171149   

TargetCaspase-3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171149((S)-2-tert-Butyl-8-oxo-5,6,7,8-tetrahydro-1H-1,4,7...)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibitory activity towards CASP3 using fluorogenic substrates following an incubation for over 30 min at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171149((S)-2-tert-Butyl-8-oxo-5,6,7,8-tetrahydro-1H-1,4,7...)
Affinity DataIC50: 421nMAssay Description:Inhibitory activity towards CASP1 using fluorogenic substrates following an incubation for over 30 min at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171149((S)-2-tert-Butyl-8-oxo-5,6,7,8-tetrahydro-1H-1,4,7...)
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibitory activity towards CASP8 using fluorogenic substrates following an incubation for over 30 min at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed