BDBM50171148 (S)-9-Oxo-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline-1-carboxylic acid ((S)-2-hydroxy-5-oxo-tetrahydro-furan-3-yl)-amide::CHEMBL197926

SMILES OC1OC(=O)C[C@@H]1NC(=O)[C@@H]1CCc2nc3ccccc3c(=O)n12

InChI Key InChIKey=LVJUUYJFOYHIFM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171148   

TargetCaspase-3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171148((S)-9-Oxo-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity towards CASP3 using fluorogenic substrates following an incubation for over 30 min at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171148((S)-9-Oxo-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazo...)
Affinity DataIC50: 4.58E+3nMAssay Description:Inhibitory activity towards CASP1 using fluorogenic substrates following an incubation for over 30 min at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171148((S)-9-Oxo-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity towards CASP8 using fluorogenic substrates following an incubation for over 30 min at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed