BDBM50171096 CHEMBL371929::{4-[[3-Bromo-4-(difluoro-phosphono-methyl)-benzyl]-(4-[1,2,3]thiadiazol-4-yl-benzyl)-sulfamoyl]-phenoxy}-acetic acid

SMILES OC(=O)COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cc1)-c1csnn1)Cc1ccc(c(Br)c1)C(F)(F)P(O)(O)=O

InChI Key InChIKey=VYKLYBIUABMCLF-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50171096   

LigandPNGBDBM50171096({4-[[3-Bromo-4-(difluoro-phosphono-methyl)-benzyl]...)
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171096({4-[[3-Bromo-4-(difluoro-phosphono-methyl)-benzyl]...)
Affinity DataIC50: 50nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
M.S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50171096({4-[[3-Bromo-4-(difluoro-phosphono-methyl)-benzyl]...)
Affinity DataIC50: 750nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50171096({4-[[3-Bromo-4-(difluoro-phosphono-methyl)-benzyl]...)
Affinity DataKi:  53nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed