BDBM50171068 (3-Methoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-amine::CHEMBL196536

SMILES COc1cccnc1Nc1cccc(C)n1

InChI Key InChIKey=AXYSWEVLAQUWGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171068   

TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171068((3-Methoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-a...)
Affinity DataIC50: 458nMAssay Description:In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcid-sensing ion channel 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171068((3-Methoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-a...)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed