BDBM50170822 CHEMBL188592::N*6*-Cyclohexyl-N*2*-phenyl-9H-purine-2,6-diamine

SMILES C1CCC(CC1)Nc1nc(Nc2ccccc2)nc2nc[nH]c12

InChI Key InChIKey=FDFMDLSSHFEJOS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50170822   

TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170822(N*6*-Cyclohexyl-N*2*-phenyl-9H-purine-2,6-diamine ...)
Affinity DataKi:  51nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170822(N*6*-Cyclohexyl-N*2*-phenyl-9H-purine-2,6-diamine ...)
Affinity DataKi:  1.70E+3nMAssay Description:Percent inhibition of [3H]ZM241,385 binding to human adenosine A2a receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50170822(N*6*-Cyclohexyl-N*2*-phenyl-9H-purine-2,6-diamine ...)
Affinity DataKi:  2.73E+3nMAssay Description:Percent inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed