BDBM50170602 CHEMBL188462::[(E)-(S)-4-(5-Isopropoxy-pyridin-3-yl)-1-methyl-but-3-enyl]-methyl-amine

SMILES CN[C@@H](C)C\C=C\c1cncc(OC(C)C)c1

InChI Key InChIKey=RPCVIAXDAUMJJP-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50170602   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170602([(E)-(S)-4-(5-Isopropoxy-pyridin-3-yl)-1-methyl-bu...)
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha 7 in rat mid brain slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170602([(E)-(S)-4-(5-Isopropoxy-pyridin-3-yl)-1-methyl-bu...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
LigandPNGBDBM50170602([(E)-(S)-4-(5-Isopropoxy-pyridin-3-yl)-1-methyl-bu...)
Affinity DataEC50:  106nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in HEK293 cells incubated for 5 mins measured every second for 1 mins followed by every 5 secs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed