BDBM50170453 (2S,3S)-3-(4-Fluoro-phenyl)-piperidine-4-carboxylic acid {(R)-3-[6-(4-chloro-phenylsulfanyl)-2-(4-methoxy-phenyl)-3-oxo-2,3-dihydro-pyridazin-4-yl]-1-methyl-propyl}-amide::CHEMBL361883

SMILES COc1ccc(cc1)-n1nc(Sc2ccc(Cl)cc2)cc(CC[C@@H](C)NC(=O)[C@H]2CCNC[C@@H]2c2ccc(F)cc2)c1=O

InChI Key InChIKey=VLQGURFNWDTOFC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50170453   

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170453((2S,3S)-3-(4-Fluoro-phenyl)-piperidine-4-carboxyli...)
Affinity DataEC50:  110nMAssay Description:Effective concentration at human melanocortin 4 receptor in cAMP release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170453((2S,3S)-3-(4-Fluoro-phenyl)-piperidine-4-carboxyli...)
Affinity DataIC50: 66nMAssay Description:Effective concentration at human melanocortin 4 receptor in cAMP release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170453((2S,3S)-3-(4-Fluoro-phenyl)-piperidine-4-carboxyli...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of [125I]-NDP- alpha-MSH binding to human melanocortin 5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed