BDBM50170207 CHEMBL180762::[4-(2'-Hydroxy-biphenyl-4-yl)-thiophene-2-carbonyl]-carbamic acid 4-methyl-benzyl ester

SMILES Cc1ccc(COC(=O)NC(=O)c2cc(cs2)-c2ccc(cc2)-c2ccccc2O)cc1

InChI Key InChIKey=ZRYWWVOWAKCPRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170207   

TargetMacrophage metalloelastase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50170207([4-(2'-Hydroxy-biphenyl-4-yl)-thiophene-2-carbonyl...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Matrix metalloprotease-12 in presence of 5 nM acetohydroximateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50170207([4-(2'-Hydroxy-biphenyl-4-yl)-thiophene-2-carbonyl...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed