BDBM50170018 CHEMBL3805216

SMILES CC1CCN(CCCOc2ccc(=O)n(n2)-c2ccc(F)c(F)c2)CC1

InChI Key InChIKey=JTTXOMDVWFQDIN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170018   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50170018(CHEMBL3805216)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 180 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2017
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50170018(CHEMBL3805216)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells assessed as tail current at -50 mV holding potential by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2017
Entry Details Article
PubMed