BDBM50169762 (S)-1-cyclohexylpropan-2-yl (S)-1-oxo-1-(4-phenylthiazol-2-yl)hexan-2-ylcarbamate::CHEMBL181105::[(S)-1-(4-Phenyl-thiazole-2-carbonyl)-pentyl]-carbamic acid (S)-2-cyclohexyl-1-methyl-ethyl ester

SMILES CCCC[C@H](NC(=O)O[C@@H](C)CC1CCCCC1)C(=O)c1nc(cs1)-c1ccccc1

InChI Key InChIKey=ZFKNRHGBCDTQQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169762   

TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169762([(S)-1-(4-Phenyl-thiazole-2-carbonyl)-pentyl]-carb...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169762([(S)-1-(4-Phenyl-thiazole-2-carbonyl)-pentyl]-carb...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed