BDBM50169689 CHEMBL3805203

SMILES [H][C@@]12CC[C@@]([H])(CN1C(=O)c1csnn1)N(C2)c1ccc2n(CC(C)(C)C)c(=O)n(C)c2n1

InChI Key InChIKey=UXKSQZZBCSFGQA-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50169689   

TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169689(CHEMBL3805203)
Affinity DataEC50:  29nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169689(CHEMBL3805203)
Affinity DataEC50:  637nMAssay Description:Agonist activity at recombinant human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect preincubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169689(CHEMBL3805203)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169689(CHEMBL3805203)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169689(CHEMBL3805203)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169689(CHEMBL3805203)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of mGlu6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed