BDBM50169685 CHEMBL360353::N-[4-(Thiazol-2-ylcarbamoyl)-thiazol-5-yl]-malonamic acid ethyl ester

SMILES CCOC(=O)CC(=O)Nc1scnc1C(=O)Nc1nccs1

InChI Key InChIKey=OOUWLDLZLGDRQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169685   

TargetMethionine aminopeptidase(Escherichia coli (strain K12))
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50169685(N-[4-(Thiazol-2-ylcarbamoyl)-thiazol-5-yl]-malonam...)
Affinity DataIC50: 66nMAssay Description:Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Baker's yeast)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50169685(N-[4-(Thiazol-2-ylcarbamoyl)-thiazol-5-yl]-malonam...)
Affinity DataIC50: 670nMAssay Description:Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM) More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed