BDBM50169684 5-(2-Chloro-4-fluoro-benzyl)-thiazole-4-carboxylic acid thiazol-2-ylamide::CHEMBL361978

SMILES Fc1ccc(Cc2scnc2C(=O)Nc2nccs2)c(Cl)c1

InChI Key InChIKey=GOJSWWPJAAVYDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169684   

TargetMethionine aminopeptidase(Escherichia coli (strain K12))
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50169684(5-(2-Chloro-4-fluoro-benzyl)-thiazole-4-carboxylic...)
Affinity DataIC50: 82nMAssay Description:Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Baker's yeast)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50169684(5-(2-Chloro-4-fluoro-benzyl)-thiazole-4-carboxylic...)
Affinity DataIC50: 900nMAssay Description:Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM) More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed