BDBM50169675 5-(2-Pyrrolidin-1-yl-acetylamino)-thiazole-4-carboxylic acid thiazol-2-ylamide::CHEMBL178249

SMILES O=C(CN1CCCC1)Nc1scnc1C(=O)Nc1nccs1

InChI Key InChIKey=HLKRCJRWQUMSDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169675   

TargetMethionine aminopeptidase(Escherichia coli (strain K12))
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50169675(5-(2-Pyrrolidin-1-yl-acetylamino)-thiazole-4-carbo...)
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Baker's yeast)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50169675(5-(2-Pyrrolidin-1-yl-acetylamino)-thiazole-4-carbo...)
Affinity DataIC50: 860nMAssay Description:Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM) More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed