BDBM50169385 1-(3,5-Dichloro-phenyl)-3-(1-methyl-4-p-tolyl-piperidin-4-ylmethyl)-urea::CHEMBL175874

SMILES CN1CCC(CNC(=O)Nc2cc(Cl)cc(Cl)c2)(CC1)c1ccc(C)cc1

InChI Key InChIKey=XWAIJWKTDQPUKU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169385   

TargetMelanin-concentrating hormone receptor 1(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50169385(1-(3,5-Dichloro-phenyl)-3-(1-methyl-4-p-tolyl-pipe...)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50169385(1-(3,5-Dichloro-phenyl)-3-(1-methyl-4-p-tolyl-pipe...)
Affinity DataKi:  300nMAssay Description:Ability to displace [125I]-MCH()0.5 nM from human MCH1R(2.5 uM) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed