BDBM50169373 1-(3,5-Dichloro-phenyl)-3-[4-(4-pyridin-3-yl-phenyl)-piperidin-4-ylmethyl]-urea::CHEMBL175860

SMILES Clc1cc(Cl)cc(NC(=O)NCC2(CCNCC2)c2ccc(cc2)-c2cccnc2)c1

InChI Key InChIKey=LRJDGIGFZKJDPI-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169373   

TargetMelanin-concentrating hormone receptor 1(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50169373(1-(3,5-Dichloro-phenyl)-3-[4-(4-pyridin-3-yl-pheny...)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50169373(1-(3,5-Dichloro-phenyl)-3-[4-(4-pyridin-3-yl-pheny...)
Affinity DataKi:  39nMAssay Description:Ability to displace [125I]-MCH()0.5 nM from human MCH1R(2.5 uM) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed