BDBM50169367 CHEMBL3804970

SMILES Cc1noc(C)c1[C@@H]1C[C@](C)(N=C(N)S1)c1cc(NC(=O)c2ccc(Cl)cn2)c(F)cc1F

InChI Key InChIKey=YTXPWKAAQCLYBO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169367   

TargetBeta-secretase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50169367(CHEMBL3804970)
Affinity DataIC50: 31nMAssay Description:Inhibition of BACE1 in human H4 cells expressing APP751 Swedish mutant assessed as inhibition of amyloid beta 40 or amyloid beta 42 production incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2017
Entry Details Article
PubMed