BDBM50169108 2,4,6-Trifluoro-N-[(1S,2S)-2-hydroxy-3-[2-(3-methoxy-phenyl)-ethylcarbamoyl]-1-(4-thiophen-3-yl-benzyloxymethyl)-propyl]-benzamide::CHEMBL190539

SMILES COc1cccc(CCNC(=O)C[C@H](O)[C@H](COCc2ccc(cc2)-c2ccsc2)NC(=O)c2c(F)cc(F)cc2F)c1

InChI Key InChIKey=TUYZMTOTGANLMU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50169108   

TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169108(2,4,6-Trifluoro-N-[(1S,2S)-2-hydroxy-3-[2-(3-metho...)
Affinity DataKi:  221nMAssay Description:Inhibitory concentration against the plasmepsin-1 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169108(2,4,6-Trifluoro-N-[(1S,2S)-2-hydroxy-3-[2-(3-metho...)
Affinity DataKi:  693nMAssay Description:Inhibitory concentration against the plasmepsin-2 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169108(2,4,6-Trifluoro-N-[(1S,2S)-2-hydroxy-3-[2-(3-metho...)
Affinity DataKi:  1.88E+3nMAssay Description:Inhibitory concentration against the human Cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed