BDBM50169107 CHEMBL190348::N-{(1S,2S)-1-(Biphenyl-4-ylmethoxymethyl)-2-hydroxy-3-[2-(3-methoxy-phenyl)-ethylcarbamoyl]-propyl}-2,4,6-trifluoro-benzamide

SMILES COc1cccc(CCNC(=O)C[C@H](O)[C@H](COCc2ccc(cc2)-c2ccccc2)NC(=O)c2c(F)cc(F)cc2F)c1

InChI Key InChIKey=CTXDQIFHYWGFBV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50169107   

TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169107(N-{(1S,2S)-1-(Biphenyl-4-ylmethoxymethyl)-2-hydrox...)
Affinity DataKi:  116nMAssay Description:Inhibitory concentration against the plasmepsin-1 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169107(N-{(1S,2S)-1-(Biphenyl-4-ylmethoxymethyl)-2-hydrox...)
Affinity DataKi:  308nMAssay Description:Inhibitory concentration against the plasmepsin-2 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169107(N-{(1S,2S)-1-(Biphenyl-4-ylmethoxymethyl)-2-hydrox...)
Affinity DataKi: >5.90E+3nMAssay Description:Inhibitory concentration against the human Cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed