BDBM50169101 CHEMBL191487::N-[(1S,2S)-3-Cyclohexylcarbamoyl-2-hydroxy-1-(4-thiophen-3-yl-benzyloxymethyl)-propyl]-2,4,6-trifluoro-benzamide

SMILES O[C@@H](CC(=O)NC1CCCCC1)[C@H](COCc1ccc(cc1)-c1ccsc1)NC(=O)c1c(F)cc(F)cc1F

InChI Key InChIKey=WGQWSPXLSXKUKP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50169101   

TargetPlasmepsin II(Plasmodium falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169101(N-[(1S,2S)-3-Cyclohexylcarbamoyl-2-hydroxy-1-(4-th...)
Affinity DataKi:  260nMAssay Description:Inhibitory concentration against the plasmepsin-2 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169101(N-[(1S,2S)-3-Cyclohexylcarbamoyl-2-hydroxy-1-(4-th...)
Affinity DataKi:  278nMAssay Description:Inhibitory concentration against the plasmepsin-1 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50169101(N-[(1S,2S)-3-Cyclohexylcarbamoyl-2-hydroxy-1-(4-th...)
Affinity DataKi:  4.94E+3nMAssay Description:Inhibitory concentration against the human Cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed