BDBM50169088 CHEMBL3806032

SMILES CC(C)C[C@H](NC(=O)[C@@H]1Cc2ccc(Oc3cc(C[C@H](NC(=O)OCc4ccccc4)C(=O)N[C@@H](CC(C)C)C(=O)N1)ccc3[N+]([O-])=O)cc2)C=O

InChI Key InChIKey=HMEFKYRCNZDJCR-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50169088   

TargetCathepsin B(Human)
Whitman College

Curated by ChEMBL
LigandPNGBDBM50169088(CHEMBL3806032)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human liver cathepsin B using Cbz-Arg-Arg-AMC as fluorogenic substrate measured every 20 seconds for 10 mins by fluorescence based assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCalpain-1 catalytic subunit(Human)
Whitman College

Curated by ChEMBL
LigandPNGBDBM50169088(CHEMBL3806032)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of m-calpain (unknown origin) using Suc-LLVY-AMC as fluorogenic substrate measured every 20 seconds for 10 mins by fluorescence based assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCalpain-2 catalytic subunit(Human)
Whitman College

Curated by ChEMBL
LigandPNGBDBM50169088(CHEMBL3806032)
Affinity DataKi:  2.03E+3nMAssay Description:Inhibition of m-calpain (unknown origin) using Suc-LY-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetCathepsin B(Human)
Whitman College

Curated by ChEMBL
LigandPNGBDBM50169088(CHEMBL3806032)
Affinity DataKi:  3.05E+3nMAssay Description:Inhibition of human liver cathepsin B using Cbz-RR-AMC as substrate by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed