BDBM50169006 5-Ethyl-2-(2-methylaminomethyl-phenylsulfanyl)-phenylamine::CHEMBL189375

SMILES CCc1ccc(Sc2ccccc2CNC)c(N)c1

InChI Key InChIKey=XIVFNOGFYONSDE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50169006   

TargetSodium-dependent serotonin transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50169006(5-Ethyl-2-(2-methylaminomethyl-phenylsulfanyl)-phe...)
Affinity DataKi:  2.04nMAssay Description:In vitro inhibition of [3H]citalopram binding to human serotonin transporter expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50169006(5-Ethyl-2-(2-methylaminomethyl-phenylsulfanyl)-phe...)
Affinity DataKi:  445nMAssay Description:In vitro inhibition of [3H]nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50169006(5-Ethyl-2-(2-methylaminomethyl-phenylsulfanyl)-phe...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]WIN-35428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed