BDBM50168988 (2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL::CHEMBL425723

SMILES OC[C@H](NC[C@H]1NC[C@H](O)[C@@H]1O)c1ccccc1

InChI Key InChIKey=OGMKEJTXCCFISS-UHFFFAOYSA-N

Data  7 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50168988   

Targetalpha-1,2-Mannosidase(Soybean)
Institute of Chemical Sciences and Engineering

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of alpha-Mannosidase isolated from almondMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Targetalpha-1,2-Mannosidase(Soybean)
Institute of Chemical Sciences and Engineering

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataIC50: 700nMAssay Description:Concentration of compound inhibiting alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysosomal alpha-mannosidase(Human)
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLysosomal alpha-mannosidase(Human)
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLysosomal alpha-mannosidase(Human)
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Targetalpha-1,2-Mannosidase(Soybean)
Institute of Chemical Sciences and Engineering

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  135nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Targetalpha-1,2-Mannosidase(Soybean)
Institute of Chemical Sciences and Engineering

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  9.50E+3nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from AlmondMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  1.68E+4nMAssay Description:Inhibition of human ER alpha mannosidase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-mannosidase(Human)
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  2.33E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Human)
Universidade Do Porto 687

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  2.69E+4nMAssay Description:Inhibition of human golgi alpha mannosidase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-mannosidase(Human)
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  3.25E+4nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLysosomal alpha-mannosidase(Human)
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  4.15E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed