BDBM50168963 (3S,4aS,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenoxy]-decahydro-isoquinoline-3-carboxylic acid isobutyl ester::CHEMBL189721

SMILES CC(C)COC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Oc1ccccc1-c1nnn[nH]1

InChI Key InChIKey=ZOQOMMJLTPWGSU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50168963   

TargetGlutamate receptor ionotropic, kainate 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50168963((3S,4aS,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenoxy]-d...)
Affinity DataKi:  7.37E+3nMAssay Description:Inhibition of [3H]-KA binding to iontropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50168963((3S,4aS,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenoxy]-d...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50168963((3S,4aS,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenoxy]-d...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of [3H]KA binding to iontropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed