BDBM50168798 1-(2-Biphenyl-4-yl-4-cyclopentylamino-butyl)-3-(3,5-dichloro-phenyl)-urea::CHEMBL179325

SMILES Clc1cc(Cl)cc(NC(=O)NCC(CCNC2CCCC2)c2ccc(cc2)-c2ccccc2)c1

InChI Key InChIKey=FALDQSPWCQAMAR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168798   

TargetMelanin-concentrating hormone receptor 1(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50168798(1-(2-Biphenyl-4-yl-4-cyclopentylamino-butyl)-3-(3,...)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50168798(1-(2-Biphenyl-4-yl-4-cyclopentylamino-butyl)-3-(3,...)
Affinity DataKi:  50nMAssay Description:Inhibitory constant towards Human melanin-concentrating hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed