BDBM50168744 (2R,3R)-3-Hydroxy-1-[4-(2-methoxy-benzyloxy)-benzenesulfonyl]-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL187852

SMILES COc1ccccc1COc1ccc(cc1)S(=O)(=O)N1CCC[C@@](C)(O)[C@@H]1C(=O)NO

InChI Key InChIKey=NFUSRQFYPZGOLU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50168744   

LigandPNGBDBM50168744((2R,3R)-3-Hydroxy-1-[4-(2-methoxy-benzyloxy)-benze...)
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50168744((2R,3R)-3-Hydroxy-1-[4-(2-methoxy-benzyloxy)-benze...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory concentration against MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50168744((2R,3R)-3-Hydroxy-1-[4-(2-methoxy-benzyloxy)-benze...)
Affinity DataIC50: 2.57E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed