BDBM50168738 (2R,3R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL186500

SMILES Cc1ccc(F)cc1COc1ccc(cc1)S(=O)(=O)N1CCC[C@@](C)(O)[C@@H]1C(=O)NO

InChI Key InChIKey=UTAGRFZAWOLQHO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50168738   

LigandPNGBDBM50168738((2R,3R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50168738((2R,3R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50168738((2R,3R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 603nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed