BDBM50168570 (R)-7-{3-[2-Chloro-4-(tetrahydro-pyran-4-yl)-phenoxy]-propoxy}-2-ethyl-chroman-2-carboxylic acid::CHEMBL179657

SMILES CC[C@@]1(CCc2ccc(OCCCOc3ccc(cc3Cl)C3CCOCC3)cc2O1)C(O)=O

InChI Key InChIKey=OZGIFXUDSUMYLU-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50168570   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168570((R)-7-{3-[2-Chloro-4-(tetrahydro-pyran-4-yl)-pheno...)
Affinity DataIC50: 710nMAssay Description:In vitro binding affinity against human PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168570((R)-7-{3-[2-Chloro-4-(tetrahydro-pyran-4-yl)-pheno...)
Affinity DataEC50:  22nMAssay Description:Agonist activity against human PPARalpha in COS-1 cell Gal4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168570((R)-7-{3-[2-Chloro-4-(tetrahydro-pyran-4-yl)-pheno...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro binding affinity against human PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168570((R)-7-{3-[2-Chloro-4-(tetrahydro-pyran-4-yl)-pheno...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro binding affinity against human PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed