BDBM50168565 (R)-7-[3-(2-Chloro-4-trifluoromethyl-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid::CHEMBL367549

SMILES CC[C@@]1(CCc2ccc(OCCCOc3ccc(cc3Cl)C(F)(F)F)cc2O1)C(O)=O

InChI Key InChIKey=CLJITGDKQYRMGK-UHFFFAOYSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50168565   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168565((R)-7-[3-(2-Chloro-4-trifluoromethyl-phenoxy)-prop...)
Affinity DataEC50:  36nMAssay Description:Agonist activity against human PPARalpha in COS-1 cell Gal4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168565((R)-7-[3-(2-Chloro-4-trifluoromethyl-phenoxy)-prop...)
Affinity DataIC50: 90nMAssay Description:In vitro binding affinity against human PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168565((R)-7-[3-(2-Chloro-4-trifluoromethyl-phenoxy)-prop...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity against human PPARgamma in COS-1 cell Gal4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168565((R)-7-[3-(2-Chloro-4-trifluoromethyl-phenoxy)-prop...)
Affinity DataIC50: 4.30E+3nMAssay Description:In vitro binding affinity against human PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168565((R)-7-[3-(2-Chloro-4-trifluoromethyl-phenoxy)-prop...)
Affinity DataIC50: 2.30E+3nMAssay Description:In vitro binding affinity against human PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168565((R)-7-[3-(2-Chloro-4-trifluoromethyl-phenoxy)-prop...)
Affinity DataIC50: 90.0nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168565((R)-7-[3-(2-Chloro-4-trifluoromethyl-phenoxy)-prop...)
Affinity DataIC50: 2.30E+3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168565((R)-7-[3-(2-Chloro-4-trifluoromethyl-phenoxy)-prop...)
Affinity DataIC50: 4.30E+3nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed