BDBM50168564 7-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]-propoxy}-chroman-2-carboxylic acid::CHEMBL180912

SMILES OC(=O)C1CCc2ccc(OCCCOc3ccc(OCC(F)(F)F)cc3Cl)cc2O1

InChI Key InChIKey=RPDQRDHGKSEOQI-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50168564   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168564(7-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)
Affinity DataIC50: 4.10E+3nMAssay Description:In vitro binding affinity against human PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168564(7-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)
Affinity DataIC50: 810nMAssay Description:In vitro binding affinity against human PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168564(7-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)
Affinity DataEC50:  120nMAssay Description:Agonist activity against human PPARalpha in COS-1 cell Gal4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168564(7-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity against human PPARgamma in COS-1 cell Gal4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168564(7-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)
Affinity DataIC50: 6.90E+3nMAssay Description:In vitro binding affinity against human PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed