BDBM50168551 (R)-7-[3-(2-Chloro-4-fluoro-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid::CHEMBL424957

SMILES CC[C@@]1(CCc2ccc(OCCCOc3ccc(F)cc3Cl)cc2O1)C(O)=O

InChI Key InChIKey=HRLIFFYSYMIPQF-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50168551   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168551((R)-7-[3-(2-Chloro-4-fluoro-phenoxy)-propoxy]-2-et...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro binding affinity against human PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168551((R)-7-[3-(2-Chloro-4-fluoro-phenoxy)-propoxy]-2-et...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity against human PPARgamma in COS-1 cell Gal4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168551((R)-7-[3-(2-Chloro-4-fluoro-phenoxy)-propoxy]-2-et...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro binding affinity against human PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168551((R)-7-[3-(2-Chloro-4-fluoro-phenoxy)-propoxy]-2-et...)
Affinity DataIC50: 4.30E+3nMAssay Description:In vitro binding affinity against human PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed