BDBM50168549 (R)-7-[3-(2-Chloro-4-spiro[2.5]oct-6-yl-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid::CHEMBL176222

SMILES CC[C@@]1(CCc2ccc(OCCCOc3ccc(cc3Cl)C3CCC4(CC4)CC3)cc2O1)C(O)=O

InChI Key InChIKey=AOWBYHGZFBMURE-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50168549   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168549((R)-7-[3-(2-Chloro-4-spiro[2.5]oct-6-yl-phenoxy)-p...)
Affinity DataEC50:  300nMAssay Description:Agonist activity against human PPARalpha in COS-1 cell Gal4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168549((R)-7-[3-(2-Chloro-4-spiro[2.5]oct-6-yl-phenoxy)-p...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro binding affinity against human PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168549((R)-7-[3-(2-Chloro-4-spiro[2.5]oct-6-yl-phenoxy)-p...)
Affinity DataIC50: 3.70E+3nMAssay Description:In vitro binding affinity against human PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168549((R)-7-[3-(2-Chloro-4-spiro[2.5]oct-6-yl-phenoxy)-p...)
Affinity DataIC50: 610nMAssay Description:In vitro binding affinity against human PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168549((R)-7-[3-(2-Chloro-4-spiro[2.5]oct-6-yl-phenoxy)-p...)
Affinity DataEC50:  500nMAssay Description:Agonist activity against human PPARgamma in COS-1 cell Gal4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed