BDBM50168547 (R)-7-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid::CHEMBL360992

SMILES C[C@@]1(CCc2ccc(OCCCOc3ccc(OC(F)(F)F)cc3Cl)cc2O1)C(O)=O

InChI Key InChIKey=WUWGFTGOXMGELJ-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50168547   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168547((R)-7-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)
Affinity DataIC50: 57nMAssay Description:In vitro binding affinity against human PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168547((R)-7-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)
Affinity DataEC50:  20nMAssay Description:Agonist activity against human PPARalpha in COS-1 cell Gal4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168547((R)-7-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro binding affinity against human PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50168547((R)-7-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)
Affinity DataIC50: 490nMAssay Description:In vitro binding affinity against human PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed