BDBM50168255 (+/-)6-(2-Phenylethyl)nicotine::5-(1-Methyl-pyrrolidin-2-yl)-2-phenethyl-pyridine::CHEMBL190295

SMILES CN1CCCC1c1ccc(CCc2ccccc2)nc1

InChI Key InChIKey=YJFYNYHEHYBROJ-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50168255   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50168255((+/-)6-(2-Phenylethyl)nicotine | 5-(1-Methyl-pyrro...)
Affinity DataKi:  15nMAssay Description:Inhibition of [3H](-)-nicotine binding to rat brain (minus cerebellum) Nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50168255((+/-)6-(2-Phenylethyl)nicotine | 5-(1-Methyl-pyrro...)
Affinity DataKi:  15nMAssay Description:Binding affinity for rat brain Nicotinic acetylcholine receptor alpha4-beta2 using [3H]S-(-)-nicotineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50168255((+/-)6-(2-Phenylethyl)nicotine | 5-(1-Methyl-pyrro...)
Affinity DataKi:  200nMAssay Description:Inhibition of [3H]epibatidine binding to rat Nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50168255((+/-)6-(2-Phenylethyl)nicotine | 5-(1-Methyl-pyrro...)
Affinity DataKi:  400nMAssay Description:Binding affinity for rat Nicotinic acetylcholine receptor alpha4-beta4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50168255((+/-)6-(2-Phenylethyl)nicotine | 5-(1-Methyl-pyrro...)
Affinity DataKi:  490nMAssay Description:Binding affinity for rat Nicotinic acetylcholine receptor alpha2-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-4(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50168255((+/-)6-(2-Phenylethyl)nicotine | 5-(1-Methyl-pyrro...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity for rat Nicotinic acetylcholine receptor alpha2-beta4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50168255((+/-)6-(2-Phenylethyl)nicotine | 5-(1-Methyl-pyrro...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity for rat Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50168255((+/-)6-(2-Phenylethyl)nicotine | 5-(1-Methyl-pyrro...)
Affinity DataKi:  4.60E+3nMAssay Description:Binding affinity for rat Nicotinic acetylcholine receptor alpha3-beta4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50168255((+/-)6-(2-Phenylethyl)nicotine | 5-(1-Methyl-pyrro...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed