BDBM50168142 CHEMBL3716578::US10849901, Compound 38::US10953012, Example 9

SMILES [O-][N+](=O)c1ccc(cc1)-c1cc(=O)n2nc(Cc3ccccc3)c(-c3ccc(Cl)cc3)c2[nH]1

InChI Key InChIKey=GUUWHOSUKOCRHG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50168142   

TargetLong-chain fatty acid transport protein 2(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50168142(CHEMBL3716578 | US10849901, Compound 38 | US109530...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of FATP2 in human HepG2 cells assessed as decrease in fatty acid transport after 5 mins by trypan blue dye based fluorescence quenching me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2017
Entry Details Article
PubMed
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM50168142(CHEMBL3716578 | US10849901, Compound 38 | US109530...)
Affinity DataIC50: 1.80nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
Go to US Patent

TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM50168142(CHEMBL3716578 | US10849901, Compound 38 | US109530...)
Affinity DataIC50: 1.40nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
Go to US Patent

LigandPNGBDBM50168142(CHEMBL3716578 | US10849901, Compound 38 | US109530...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent