BDBM50168097 CHEMBL3798135

SMILES OC(=O)CCNC(=O)c1ccc2C(CCc2c1)n1nc(cc1-c1ccc(F)cc1)-c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=HJIJRAAIWKMTEJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168097   

TargetGlucagon receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50168097(CHEMBL3798135)
Affinity DataIC50: 8.90E+3nMAssay Description:Displacement of [125I]-glucagon from wild type human glucagon receptor expressed in CHO-K1 cells after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2017
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50168097(CHEMBL3798135)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at wild type human glucagon receptor expressed in HEK293T cells assessed as inhibition of glucagon-induced cAMP accumulation incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2017
Entry Details Article
PubMed