BDBM50167795 1-(4-fluorophenyl)-4',4a,5'-trimethyl-(4'R,4aS,5'R)-spiro[1,4,4a,5,6,7-hexahydrocyclopenta[f]indazole-5,2'-(dihydro[1,3]dioxolane)]::CHEMBL194012

SMILES C[C@H]1OC2(CCC3=Cc4c(C[C@]23C)cnn4-c2ccc(F)cc2)O[C@@H]1C

InChI Key InChIKey=SQWQGCCFUAYKKJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50167795   

TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167795(1-(4-fluorophenyl)-4',4a,5'-trimethyl-(4'R,4aS,5'R...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167795(1-(4-fluorophenyl)-4',4a,5'-trimethyl-(4'R,4aS,5'R...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for human estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167795(1-(4-fluorophenyl)-4',4a,5'-trimethyl-(4'R,4aS,5'R...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for rat mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167795(1-(4-fluorophenyl)-4',4a,5'-trimethyl-(4'R,4aS,5'R...)
Affinity DataIC50: 24nMAssay Description:Binding affinity for human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167795(1-(4-fluorophenyl)-4',4a,5'-trimethyl-(4'R,4aS,5'R...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity for human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167795(1-(4-fluorophenyl)-4',4a,5'-trimethyl-(4'R,4aS,5'R...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human glucocorticoid receptor alpha isoform More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed