BDBM50167622 (2R,5R)-1-[4-(2-Bromo-benzyloxy)-benzenesulfonyl]-5-hydroxy-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL372261

SMILES CC1(C)C[C@@H](O)CN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2Br)cc1

InChI Key InChIKey=MRBPTYYVXXZQBB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50167622   

TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167622((2R,5R)-1-[4-(2-Bromo-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50: 715nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50167622((2R,5R)-1-[4-(2-Bromo-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167622((2R,5R)-1-[4-(2-Bromo-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed