BDBM50167085 CHEMBL3799623

SMILES Oc1cn(ccc1=O)-c1cc(ccn1)-c1cnn(Cc2ccccc2)c1

InChI Key InChIKey=ZGZVBPHOEZGAFJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50167085   

TargetLanosterol synthase(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50167085(CHEMBL3799623)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2017
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50167085(CHEMBL3799623)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2017
Entry Details Article
PubMed